Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2) Rat IgG2a Recombinant Antibody Proteintech 65663-1-TR
$299.00
In stock
SKU
65663-1-TR
H2Aa, Aalpha, H 2Aa, H2-Aa, Ia 1
| Formulation:：PBS, Azide | Formulation:：PBS, Azide1 |
| Applications：Flow Cytometry (FC) | Formulation:：PBS, Azide2 |
| Reactivity：Rat / IgG2a | Formulation:：PBS, Azide3 |
| Type：N/A Predict reactive species | Formulation:：PBS, Azide4 |
| RRID：Unconjugated | Formulation:：PBS, Azide5 |
| Storage Buffer：PBS with 0.09% sodium azide, pH 7.3. | Formulation:：PBS, Azide6 |
| Background Information：Major histocompatibility complex (MHC) class II molecules are heterodimeric transmembrane glycoproteins that are expressed on the surface of antigen-presenting cells such as dendritic cells, macrophages, and B cells. The M5/114.15.2 antibody detects polymorphic determinants present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2b, H-2d, H-2q, H-2p, H-2r and H-2u haplotypes but not from mice carrying the H-2s or H-2f haplotypes (PMID: 6170707). This antibody recognizes both I-A and I-E subregion-encoded Ia glycoproteins (I-Ab, I-Ad, I-Aq, I-Ed, I-Ek, not I-Af, I-Ak, or I-As). M5/114 antibody is reported to inhibit I-A subregion-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not the H-2f, H-2k, H-2s haplotypes (PMID: 6173436). | Formulation:：PBS, Azide7 |
| biogegep8 | Formulation:：PBS, Azide8 |
| biogegep9 | Formulation:：PBS, Azide9 |
| Formulation:：PBS, Azide0 | Applications：Flow Cytometry (FC)0 |
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