Anti-Human MICA/MICB (6D4) Mouse IgG2a Recombinant Antibody Proteintech 65589-1-MR

$299.00
In stock
SKU
65589-1-MR

 

MICB, MICA, 6D4, MIC A, MIC-A

Formulation::PBS, Azide Formulation::PBS, Azide1
Applications:Flow Cytometry (FC) Formulation::PBS, Azide2
 Reactivity:Mouse / IgG2a Formulation::PBS, Azide3
Type:Transfected C1R cells expressing MICA Predict reactive species Formulation::PBS, Azide4
RRID:100507436 Formulation::PBS, Azide5
Storage Buffer:Protein A purification Formulation::PBS, Azide6
Background Information:Human MHC class I chain-related genes located within the HLA class I region of chromosome 6 encode MHC class I chain-related A and B (MICA and MICB) (PMID: 11429322). MICA and MICB are stress-inducible surface molecules that are not associated with β2-microglobulin and do not present peptides (PMID: 9497295). They are expressed in intestinal epithelium and many epithelial tumors (PMID: 10359807). MICA and MICB are ligands for NKG2D which is an activating receptor that is expressed on most natural killer (NK) cells, CD8 αβ T cells, and γδ T cells (PMID: 10426993; 11491531). The monoclonal antibody 6D4 recognizes MICA and MICB. Formulation::PBS, Azide7
biogegep8 Formulation::PBS, Azide8
biogegep9 Formulation::PBS, Azide9
Formulation::PBS, Azide0 Applications:Flow Cytometry (FC)0

 

 

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