Beta Catenin Monoclonal antibody Proteintech 66379-1-Ig
$299.00
In stock
SKU
66379-1-Ig
1B8A1, b cat, B-catenin, beta-Catenin, Catenin beta 1
| Formulation::PBS, Azide, Glycerol | Formulation::PBS, Azide, Glycerol1 |
| Applications:Western Blot (WB) | Formulation::PBS, Azide, Glycerol2 |
| Reactivity:Human, Mouse, Rat, Pig, Chicken, Sheep | Formulation::PBS, Azide, Glycerol3 |
| Type:Antibody | Formulation::PBS, Azide, Glycerol4 |
| RRID:NM_001904 | Formulation::PBS, Azide, Glycerol5 |
| Storage Buffer:AB_2857358 | Formulation::PBS, Azide, Glycerol6 |
| Background Information:β-Catenin, also known as CTNNB1, is an evolutionarily conserved, multifunctional intracellular protein. β-Catenin was originally identified in cell adherens junctions (AJs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the AJs, β-catenin is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. The Wnt/β-catenin pathway is also involved in the activation of other intracellular messengers such as calcium fluxes, JNK, and SRC kinases. Deregulation of β-catenin activity is associated with multiple diseases including cancers. (PMID: 22617422; 18334222) | Formulation::PBS, Azide, Glycerol7 |
| biogegep8 | Formulation::PBS, Azide, Glycerol8 |
| biogegep9 | Formulation::PBS, Azide, Glycerol9 |
| Formulation::PBS, Azide, Glycerol0 | Applications:Western Blot (WB)0 |