KRAS Polyclonal antibody Proteintech 12063-1-AP

$299.00
In stock
SKU
12063-1-AP

 

pan RAS, C K RAS, c Ki ras, c-Ki-ras, c-K-ras

Formulation::PBS, Azide, Glycerol Formulation::PBS, Azide, Glycerol1
Applications:Western Blot (WB) Formulation::PBS, Azide, Glycerol2
 Reactivity:Human, Mouse, Rat, Chicken, Zebrafish Formulation::PBS, Azide, Glycerol3
Type:Antibody Formulation::PBS, Azide, Glycerol4
RRID:BC013572 Formulation::PBS, Azide, Glycerol5
Storage Buffer:Unconjugated Formulation::PBS, Azide, Glycerol6
Background Information:KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Formulation::PBS, Azide, Glycerol7
biogegep8 Formulation::PBS, Azide, Glycerol8
biogegep9 Formulation::PBS, Azide, Glycerol9
Formulation::PBS, Azide, Glycerol0 Applications:Western Blot (WB)0

 

 

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