FcZero-rAb? APC Anti-Rat CD11b/c (OX42) Rabbit IgG Recombinant Antibody Proteintech APC-FcA65606
$299.00
In stock
SKU
APC-FcA65606
Cd11b, integrin alpha M, Itgam, OX42
| Formulation::PBS, Azide, BSA | Formulation::PBS, Azide, BSA1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide, BSA2 |
| Reactivity:Rabbit / IgG | Formulation::PBS, Azide, BSA3 |
| Type:Rat peritoneal macrophages Predict reactive species | Formulation::PBS, Azide, BSA4 |
| RRID:25021 | Formulation::PBS, Azide, BSA5 |
| Storage Buffer:Protein A purification | Formulation::PBS, Azide, BSA6 |
| Background Information:Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b (integrin alpha M or CR3A) and CD11c (integrin alpha X) are members of the integrin alpha chain family and can form α/β heterodimers with CD18 (integrin β2). CD11b/CD18 is a receptor for the complement protein fragment C3bi, and is also a receptor for fibrinogen, factor X, and ICAM1 (PMID: 2971974; 15485828). CD11c/CD18 acts as a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). The OX-42 antibody recognizes a common epitope shared between CD11b and CD11c. It binds to C3bi receptor and is known to block C3bi binding (PMID: 3512425; 8449218). | Formulation::PBS, Azide, BSA7 |
| biogegep8 | Formulation::PBS, Azide, BSA8 |
| biogegep9 | Formulation::PBS, Azide, BSA9 |
| Formulation::PBS, Azide, BSA0 | Applications:Flow Cytometry (FC)0 |