Anti-Mouse LAG-3/CD223 (C9B7W) Proteintech 65098-1-Ig
$299.00
In stock
SKU
65098-1-Ig
CD223, LAG-3, Ly66, Lag3, LAG 3
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide2 |
| Reactivity:Rat / IgG1, kappa | Formulation::PBS, Azide3 |
| Type:Murine CD223-Ig fusion protein Predict reactive species | Formulation::PBS, Azide4 |
| RRID:AB_2918400 | Formulation::PBS, Azide5 |
| Storage Buffer:Q61790 | Formulation::PBS, Azide6 |
| Background Information:Lymphocyte activation gene 3 protein (LAG-3), also known as CD223, is a type I transmembrane protein belonging to the immunoglobulin superfamily (PMID: 1692078). It is a CD4-related molecule that binds MHC class II with high affinity (PMID: 1692078; 9159144). LAG-3 is expressed on activated T and NK cells. Besides, natural CD4(+)CD25(+) Tregs express LAG-3 upon activation (PMID: 15485628). LAG-3 negatively regulates T-cell function and homeostasis, and contributes to the suppressor activity of Tregs (PMID: 14644131; 15485628). | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Flow Cytometry (FC)0 |