Anti-Mouse LAG-3/CD223 (C9B7W) Proteintech 65098-1-Ig

$299.00
In stock
SKU
65098-1-Ig

 

CD223, LAG-3, Ly66, Lag3, LAG 3

Formulation::PBS, Azide Formulation::PBS, Azide1
Applications:Flow Cytometry (FC) Formulation::PBS, Azide2
 Reactivity:Rat / IgG1, kappa Formulation::PBS, Azide3
Type:Murine CD223-Ig fusion protein Predict reactive species Formulation::PBS, Azide4
RRID:AB_2918400 Formulation::PBS, Azide5
Storage Buffer:Q61790 Formulation::PBS, Azide6
Background Information:Lymphocyte activation gene 3 protein (LAG-3), also known as CD223, is a type I transmembrane protein belonging to the immunoglobulin superfamily (PMID: 1692078). It is a CD4-related molecule that binds MHC class II with high affinity (PMID: 1692078; 9159144). LAG-3 is expressed on activated T and NK cells. Besides, natural CD4(+)CD25(+) Tregs express LAG-3 upon activation (PMID: 15485628). LAG-3 negatively regulates T-cell function and homeostasis, and contributes to the suppressor activity of Tregs (PMID: 14644131; 15485628). Formulation::PBS, Azide7
biogegep8 Formulation::PBS, Azide8
biogegep9 Formulation::PBS, Azide9
Formulation::PBS, Azide0 Applications:Flow Cytometry (FC)0

 

 

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