Anti-Mouse IFN-gamma (XMG1.2) Proteintech 65153-1-Ig
$299.00
In stock
SKU
65153-1-Ig
IFN gamma, Ifng, Ifg, IFN g, IFN γ
| Formulation:：PBS, Azide | Formulation:：PBS, Azide1 |
| Applications：Flow Cytometry (FC) (INTRA) | Formulation:：PBS, Azide2 |
| Reactivity：Rat / IgG1, kappa | Formulation:：PBS, Azide3 |
| Type：Purified Recombinant Mouse IFN gamma Predict reactive species | Formulation:：PBS, Azide4 |
| RRID：15978 | Formulation:：PBS, Azide5 |
| Storage Buffer：Affinity purification | Formulation:：PBS, Azide6 |
| Background Information：Interferon gamma (IFN γ), is a type II interferon that provides immunity against bacterial, viral and protozoan infections. In its active form, IFN γ is a glycosylated, non-covalently linked homodimer of 29-32 kDa subunits. It is produced by a number of immune cell types including natural killer cells, natural killer T cells, and effector lymphocyte T cells following antigenic and inflammatory triggers. The IFN γ dimer binds to its cognate receptor which has two subunits: IFN-γR1 which is the ligand-binding chain (α chain) and IFN-γR2, the signal-transducing chain (β chain). Binding to the receptor activates the JAK/STAT pathway which in turn activates IFN γ responsive genes. While IFN γ can inhibit viral replication, it also works as an immune-modulator and immune-stimulator by increasing surface expression of class I MHC proteins. (PMID: 19268625; 10688427) | Formulation:：PBS, Azide7 |
| biogegep8 | Formulation:：PBS, Azide8 |
| biogegep9 | Formulation:：PBS, Azide9 |
| Formulation:：PBS, Azide0 | Applications：Flow Cytometry (FC) (INTRA)0 |
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