Anti-Mouse E-cadherin (DECMA-1) Proteintech 65241-1-Ig
$299.00
In stock
SKU
65241-1-Ig
CD324 (E-cadherin), cadherin 1, Cdh1, Ecad, L CAM
| Formulation:：PBS, Azide | Formulation:：PBS, Azide1 |
| Applications：Immunofluorescence (IF)-P | Formulation:：PBS, Azide2 |
| Reactivity：Rat / IgG1, kappa | Formulation:：PBS, Azide3 |
| Type：Mouse embryonal carcinoma cell line PCC4 Aza RI Predict reactive species | Formulation:：PBS, Azide4 |
| RRID：AB_2935150 | Formulation:：PBS, Azide5 |
| Storage Buffer：P09803 | Formulation:：PBS, Azide6 |
| Background Information：Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. E-cadherin (epithelial cadherin), also known as CDH1 (cadherin 1) or CAM 120/80, is a classical member of the cadherin superfamily which also include N-, P-, R-, and B-cadherins. It has been regarded as a marker for spermatogonial stem cells in mice(PMID:23509752). E-cadherin is expressed on the cell surface in most epithelial tissues. The extracellular region of E-cadherin establishes calcium-dependent homophilic trans binding, providing specific interaction with adjacent cells, while the cytoplasmic domain is connected to the actin cytoskeleton through the interaction with p120-, α-, β-, and γ-catenin (plakoglobin). E-cadherin is important in the maintenance of the epithelial integrity, and is involved in mechanisms regulating proliferation, differentiation, and survival of epithelial cell. E-cadherin may also play a role in tumorigenesis. It is considered to be an invasion suppressor protein and its loss is an indicator of high tumor aggressiveness. | Formulation:：PBS, Azide7 |
| biogegep8 | Formulation:：PBS, Azide8 |
| biogegep9 | Formulation:：PBS, Azide9 |
| Formulation:：PBS, Azide0 | Applications：Immunofluorescence (IF)-P0 |
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