Anti-Mouse CD48 (HM48-1) Proteintech 65227-1-Ig

$299.00
In stock
SKU
65227-1-Ig

 

BLAST, BLAST 1, BLAST1, CD48 antigen, HM48-1

Formulation::PBS, Azide Formulation::PBS, Azide1
Applications:Flow Cytometry (FC) Formulation::PBS, Azide2
 Reactivity:Armenian Hamster / IgG Formulation::PBS, Azide3
Type:Mouse T lymphoma MBL-2 Predict reactive species Formulation::PBS, Azide4
RRID:AB_2935145 Formulation::PBS, Azide5
Storage Buffer:P18181 Formulation::PBS, Azide6
Background Information:Signaling lymphocytic activation molecule family 2 (SLAMF2, CD48) is an adhesion and costimulatory molecule expressed constitutively on most hematopoietic cells, particularly in antigen-presenting cells (APC). CD48 is expressed on all the hematopoietic cells, both in humans and mice, except for murine neutrophils and long-term HSC. CD48 exists as both a membrane-bound (mCD48) and a soluble (sCD48) form. CD48 can activate T cells, antigen-presenting cells and granulocytes, by binding to CD2 or bacterial FimH, and through cell intrinsic effects. Interactions between CD48 and its high-affinity ligand CD244 are more complex, with both stimulatory and inhibitory outcomes. CD48 expression is increased in autoimmunity and allergy diseases, and anti-CD48 monoclonal antibodies have been shown to attenuate experimental autoimmune encephalomyelitis. Formulation::PBS, Azide7
biogegep8 Formulation::PBS, Azide8
biogegep9 Formulation::PBS, Azide9
Formulation::PBS, Azide0 Applications:Flow Cytometry (FC)0

 

 

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