Anti-Mouse CD117/c-Kit (2B8) Proteintech 65054-1-Ig

$299.00
In stock
SKU
65054-1-Ig

 

CD117, Kit, 2B8, c KIT

Formulation::PBS, Azide Formulation::PBS, Azide1
Applications:Flow Cytometry (FC) Formulation::PBS, Azide2
 Reactivity:Rat / IgG2b, kappa Formulation::PBS, Azide3
Type:Mouse IL-3-dependent bone marrow mast cells Predict reactive species Formulation::PBS, Azide4
RRID:AB_2918362 Formulation::PBS, Azide5
Storage Buffer:P05532 Formulation::PBS, Azide6
Background Information:CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early haemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628). Formulation::PBS, Azide7
biogegep8 Formulation::PBS, Azide8
biogegep9 Formulation::PBS, Azide9
Formulation::PBS, Azide0 Applications:Flow Cytometry (FC)0

 

 

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