Anti-Mouse CD117/c-Kit (2B8) Proteintech 65054-1-Ig
$299.00
In stock
SKU
65054-1-Ig
CD117, Kit, 2B8, c KIT
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide2 |
| Reactivity:Rat / IgG2b, kappa | Formulation::PBS, Azide3 |
| Type:Mouse IL-3-dependent bone marrow mast cells Predict reactive species | Formulation::PBS, Azide4 |
| RRID:AB_2918362 | Formulation::PBS, Azide5 |
| Storage Buffer:P05532 | Formulation::PBS, Azide6 |
| Background Information:CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early haemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628). | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Flow Cytometry (FC)0 |