Anti-Human TRPV4 Rabbit Recombinant Antibody Proteintech 98690-1-RR
$299.00
In stock
SKU
98690-1-RR
Osm 9 like TRP channel 4, Osm-9-like TRP channel 4, OTRPC4, TRP12, Vanilloid receptor-like channel 2
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide2 |
| Reactivity:Rabbit / IgG | Formulation::PBS, Azide3 |
| Type:Peptide Predict reactive species | Formulation::PBS, Azide4 |
| RRID:59341 | Formulation::PBS, Azide5 |
| Storage Buffer:Q9HBA0 | Formulation::PBS, Azide6 |
| Background Information:TRPV4, also called VRL2 and VROAC, belongs to the transient receptor family and TrpV subfamily. It is a non-selective calcium permeant cation channel protein which involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. It is activated by low pH, citrate and phorbol esters. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Defects in TRPV4 are the cause of brachyolmia type 3 (BRAC3), spondylometaphyseal dysplasia Kozlowski type (SMDK) and metatropic dysplasia (MTD). Multiple transcript variants encoding different isoforms have been found. | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Flow Cytometry (FC)0 |